Like magic mushroom fruiting bodies, cannabis plant material includes multiple active ingredients (cannabinoids, terpenoids, and other “minor components”), which modulate its biological and clinical properties. Often, taking a combination of those active ingredients is better than taking only one of them. Similar to how natural mushrooms offer benefits over pure psilocybin, full spectrum cannabis products (or formulations) provide benefits over single active ingredients, like pure THC or pure CBD. See also Psilocybin Formulations. See Cannabis v Magic Mushrooms Analogy.
From the article:
“Whole-plant extracts not only are more effective but also have fewer side effects than pure CBD at higher doses, Russo says. The bottom line, he says, is that “whole-cannabis extracts are going to have an advantage over pure compounds in almost every instance.”
Ms. Erickson’s article is consistent with Rolling Stone’s indication that the future of the cannabis industry will come from formulations.